VascuCel® Bioscaffold Patch

Acellular, Strong, Pliable Collagen Patch

Product Information

VascuCel is an acellular, strong, pliable collagen bioscaffold patch with optimized biocompatibility and zero aldehyde toxicity. The collagen bioscaffold patch allows for transformative repair with harmonious healing, providing long-term durability that enables native cells to successfully grow and differentiate through the entire repair.

Key Benefits
VascuCel Bioscaffold Patch
References
Models & Specs

Require fewer interventions(1)
Have the largest published data over the longest timeframe(1)
Improve hospital efficiencies overall(1)

Site Specific Transformation into the Ideal Vascular Construct

Optimized healing and clinical performance

No stimulus for thrombosis, inflammation, toxicity from aldehydes(2,3)
Harmonious healing(4,5)
No foreign body reaction, enabling endothelialization and new native tissue growth(4,5)
Terminally sterilized for reduced risk of infection - SAL10^-6 (6)

Enhanced Procedural Efficiency

Ready to use off the shelf
No rinse required
Excellent hemostasis — reducing need for hemostatic agents(7)

Improved Handling

Supple, yet strong
Pliable, conformable(7,8,9)
Easy handling and suturability(7,8,9)

Vascular Applications
Carotid endarterectomy
Femoral artery repairs
Arteriovenous access revisions

(1) Bell, Douglas, et. al. Multi-centre experience with 500 CardioCel® implants used for the repair of congenital heart defects. The Annals of Thoracic Surgery. 2019; S0003-4975(19)30843-4

(2) Neethling, WM, et al. Enhanced biostability and biocompatibility of decellularized bovine pericardium, crosslinked with an ultra-low concentration monomeric aldehyde and treated with ADAPT. The Journal of Heart Valve Disease. 2008; 17:456-463; discussion 464.

(3) Neethling WML, et al. Mitigation of Calcification and Cytotoxicity of a Glutaraldehyde-Preserved Bovine Pericardial Matrix: Improved Biocompatibility After Extended Implantation in the Subcutaneous Rat Model. The Journal of Heart Valve Disease. 2010; 19:778-785.

(4) Brizard et al. (December 2014). New engineering treatment of bovine pericardium confers outstanding resistance to calcification in mitral and pulmonary implantations in a juvenile sheep model. The Journal of Thoracic and Cardiovascular Surgery. Vol 148, No 6, Pgs 3194-3201.

(5) Neethling, WM. Transdifferentiation and remodeling of a tissue-engineered collagen scaffold in the ovine carotid model: an experimental pilot study. Journal of Vascular Surgery. 2017; 65(Supple):195S

(6) AAMI/ISO 11737-2: Sterilization of medical devices—Microbiological methods, Part 2: Tests of sterility performed in the validation of a sterilization process.

(7) Neethling, WM, et al. Evaluation of a tissue-engineered bovine pericardial patch in paediatric patients with congenital cardiac anomalies: initial experience with the ADAPT-treated CardioCel® patch. Interactive CardioVascular and Thoracic Surgery 2013;1–5.

(8) Nelms, Justin, et al Carotid Patch Angioplasty with a novel collagen scaffold following carotid endarterectomy; 2016.

(9) Muto A, MD, PhD, el al. Journal of Vascular Surgery. 2009 July; 50(1):206-213.

USA & Canada